Creatinine Clearance
Calculate creatinine clearance using the Cockcroft-Gault equation with optional adjusted body weight. Widely used for drug dose adjustments in renal impairment.
CrCl (mL/min)
82.6
Educational tool. Not a substitute for clinical judgment, professional diagnosis, or treatment. Always verify with current guidelines.
How to use the creatinine clearance
Enter age, weight in kg, serum creatinine in mg/dL, and sex. Cockcroft-Gault estimates creatinine clearance in mL/min.
Formula & explanation
CrCl = ((140 − age) × weight × (0.85 if female)) ÷ (72 × Scr).
Examples
Age 55, 70 kg, male, Scr 1.0 → CrCl ≈ 82.6 mL/min.
Frequently asked questions
- When to use Cockcroft-Gault vs. eGFR?
- Many drug-dosing references (especially nephrotoxic drugs) still cite Cockcroft-Gault. Use the formula your reference specifies.
- Obese patients?
- Consider adjusted body weight (e.g., IBW + 0.4 × (TBW − IBW)) for more accurate estimates in obesity.
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